Pregnancy with Gilbert Syndrome – A Case Report
Published: June 1, 2014 | DOI: https://doi.org/10.7860/JCDR/2014/.4426
Mini Mohan, Lakshmi Sailaja P, Peddireddy Vijaya Narasimha Reddy
1. Consultant, Department of Obstetrics and Gynaecology, Durgabai Deshmukh Hospital, Diplomate of National Board,
Vidya Nagar, Hyderabad, Andhra Pradesh, India.
2. Registrar, Department of Obstetrics and Gynaecology, Durgabai Deshmukh Hospital, Diplomate of National Board,
Vidya Nagar, Hyderabad, Andhra Pradesh, India.
3. Assistant Professor, Department of General Medicine, Rajiv Gandhi Institute of Medical Sciences,
NTR University of Health Sciences, Putlampally, Kadapa, Andhra Pradesh, India.
Correspondence
Dr. Mini Mohan,
#102, Rose Garden Apartment, R.K. Nagar, Bagh Amber Pet, Hyderabad-13, Andhra Pradesh, India.
Phone: +91 9912957918, E-mail: minijayap@yahoo.co.uk
A primigravida presented to us at 32 weeks of gestation with vomiting, myalgia and jaundice. On examination she had icterus, she was dehydrated, uterus was corresponding to dates and the fetal heart rate was good. On evaluation, all the investigations were normal except mild unconjugated hyperbilirubinaemia and hypoglycaemia. Based on the above findings we derived at a diagnosis of Gilbert syndrome. Dehydration due to vomiting aggravated her jaundice. On correcting her dehydration jaundice resolved, patient improved symptomatically and was discharged two days later. She was later admitted at term and underwent emergency caesarian section in view of fetal distress. Mother and baby were fine postoperatively and was discharged on the fifth postoperative day Gilbert syndrome is rare in obstetric practice. Virtually all patients have decreased activity of Uridine diphosphate glucuronosyl transferase (UDPGT). The case is reported due to its rarity.
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